TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE

TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE - Names and Identifiers

Name	TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE
Synonyms	N-Boc-5-bromoindole 1-BOC-5-bromoindole 5-Bromo-1-tert-butoxycarbonylindole 5-Bromo-1-(t-Butoxycarbonyl)-1H-indole TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE 5-BROMO-1-(TERT-BUTOXYCARBONYL)-1H-INDOLE TERT-BUTYL 5-BROMO-1H-INDOLE-1-CARBOXYLATE 5-bromo-1-indolecarboxylic acid tert-butyl ester
CAS	182344-70-3
InChI	InChI=1/C13H14BrNO2/c1-13(2,3)17-12(16)15-7-6-9-8-10(14)4-5-11(9)15/h4-8H,1-3H3

TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE - Physico-chemical Properties

Molecular Formula	C13H14BrNO2
Molar Mass	296.16
Density	1.37±0.1 g/cm3(Predicted)
Melting Point	56-57°C(lit.)
Boling Point	367.9±34.0 °C(Predicted)
Flash Point	176.3°C
Vapor Presure	1.33E-05mmHg at 25°C
Appearance	Solid
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.576
Physical and Chemical Properties	WGK Germany:3

TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3

TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE - Introduction

TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE is an organic compound that has the following properties:
1. Appearance: White crystalline solid.
2. Molecular formula: C13H14BrNO2.
3. Molecular weight: 297.17g/mol.
4. Melting point: About 180-182 degrees Celsius.

The main use of TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE is as an intermediate in organic synthesis. It can be used to synthesize indole compounds, which are commonly used in drug synthesis, natural product synthesis and other fields. The Boc protecting group of TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE can play a protective role during the synthesis to protect the active nucleophilic site from interference.

The preparation method of TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE generally includes the following steps:
1.5-bromoindole reacts with 1-hydroxymethyl cyclopropylamine to generate the corresponding nucleophile.
2. Reacting a nucleophile with a N-Boc protecting reagent to obtain the TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE.

When using the TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE, you need to pay attention to its safety information:
1. This compound may have certain toxicity to human body, should avoid direct contact with skin and inhalation of its dust.
2. During operation, it is recommended to wear appropriate protective gloves and glasses to ensure good ventilation.
3. Storage should be sealed, away from the fire and oxidant.

Please note that TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE is a chemical reagent for laboratory use only and requires professional operation. Please read the relevant safety data sheets and operating instructions carefully before use.

Last Update：2024-04-09 19:05:47

MedChemExpress (MCE)

Spot supply

Product Name: N-Boc-5-bromoindole Visit Supplier Webpage Request for quotation
CAS: 182344-70-3
Tel: 609-228-6898
Email: sales@medchemexpress.com
　　　　 tech@medchemexpress.com
Mobile: 609-228-6898